Get down to business

Get down to the nitty gritty.

Health information technology data standards get down to business: maturation within domains and the emergence of interoperability

Health information technology (HIT) standards are not new. Arguably, they date to the canonical list for causes of death in the London Bills of Mortality of 1528, which was later formalized during the middle of the 19th century into what we now recognize as the International Classifications of Diseases (ICD). Beginning in the middle of the 20th century, HIT standards evolved beyond vital statis...

Business Process Simulation : How to get it right ?

Although simulation is typically considered as relevant and highly applicable, in reality the use of simulation is limited. Many organizations have tried to use simulation to analyze their business processes at some stage. However, few are using simulation in a structured and effective manner. This may be caused by a lack of training and limitations of existing tools, but in this paper we will ...

Primary care research conducted in networks: getting down to business.

This seventh annual practice-based research theme issue of the Journal of the American Board of Family Medicine highlights primary care research conducted in practice-based research networks (PBRNs). The issue includes discussion of (1) theoretical and methodological research, (2) health care research (studies addressing primary care processes), (3) clinical research (studies addressing the imp...

How to get from here to there: tracking down invasive glioma cells.

Glioblastoma (GBM) is the most common malignant primary brain tumor and one of the most lethal human cancers, with a median survival of less than 16 months for treated patients (1). Various biological properties of GBMs contribute to the failure of current treatments, including the relative radiation/drug resistance of the glioma stem cell (GSC) subpopulation, intratumoral clonal hetero-geneity...